根據26名確診瑯琊病毒患者的調查,得出染病者主要的症狀會有發燒(100%)、疲勞(54%)、咳嗽(50%)、食慾不振(50%)、肌肉痠痛(46%)、噁心(38%)、頭痛(35%)、嘔吐(35%),多數患者還會有白血球低下、血小板低下、肝功能異常和腎功能異常等狀況;目前醫療界推測,瑯琊病毒可能會誘發致死疾病,不過尚無人傳人的證據
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